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This is SKIN1004's ampoule combining Madagascar centella with 10% niacinamide, one of the more potent formulations in their line. Where SKIN1004's other centella products focus primarily on calming, this ampoule adds meaningful niacinamide concentration for brightening, pore refinement, and sebum regulation benefits. 10% niacinamide is the clinical sweet spot for most efficacy data, making this more targeted at active concerns than gentler centella-only formulations. At $37.68 for 30ml, this sits in the mid-premium ampoule tier.
The combination makes particular sense for acne-prone users. Centella calms inflammation and supports healing, directly addressing the post-inflammatory component of acne. Niacinamide reduces sebum production and pore appearance while also fading post-acne marks. The two actives work on different phases of the acne cycle simultaneously, making this more functional than either active alone for breakout-prone skin.
Madagascar centella (madecassoside, asiaticoside, and related compounds) reduces inflammation and supports healing. 10% niacinamide blocks melanin transfer (fading dark marks), reduces pore appearance, and regulates sebum production. Supporting ingredients include hydration humectants and barrier lipids. Over 6 to 12 weeks of consistent use, expect reduced active breakouts, fading post-acne marks, and more balanced oil production.
Apply after toner, before moisturizer. Dispense 3 to 4 drops, press into clean skin. Use AM and PM. For sensitive skin new to niacinamide: start PM-only for 1 to 2 weeks, then add AM.
For acne routines: pair with BHA in alternating steps (BHA AM, this ampoule PM; or BHA 3x weekly, ampoule daily).
For most skin types, 10% is well-tolerated. A subset of users experiences flushing; these users benefit from 5% alternatives or buffered formulations. The centella in this product helps reduce niacinamide flushing risk.
Jumiso: 10% niacinamide alone at $18 for 40ml. SKIN1004: 10% niacinamide plus centella at $37.68 for 30ml. For pure niacinamide: Jumiso (cheaper, simpler). For niacinamide plus centella calming: SKIN1004.
Yes. The outdated myth that they shouldn't mix has been debunked. Use vitamin C first, let absorb, then this ampoule. Layering is fine.
Reduced inflammation and active breakouts: 2 to 3 weeks. Visible pore refinement: 4 to 6 weeks. Fading post-acne marks: 8 to 12 weeks.
Niacinamide at 10% can feel slightly drying for some users. The centella and supporting hydration ingredients buffer this. Follow with a proper moisturizer to prevent dryness.
Pair with SKIN1004 HYALU-CICA Water-Fit Sun Serum for AM SPF, or Isntree Chestnut BHA Clear Toner for compound acne routine.
Browse the full SKIN1004 collection or related: Korean ampoules, best Korean products for acne-prone skin.
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