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PDRN (polydeoxyribonucleotide) is the clinical ingredient at the heart of the Rejuran skin booster injection, derived from salmon DNA. In topical skincare, PDRN is used for barrier repair and skin regeneration. medicube's PDRN Gel to Foam Cleanser brings this cosmeceutical-adjacent active into the cleansing step, combining it with gentle cleansing surfactants.
Does PDRN in a cleanser do much? With short contact time (under 2 minutes), less than in a leave-on serum. But the cleansing formula is gentle enough to avoid stripping, and the small PDRN exposure adds up over daily use. Most of the value is the gentle cleansing experience plus brand technology.
Gentle surfactants cleanse without stripping. PDRN provides modest skin regeneration support during contact. Gel-to-foam format delivers thorough cleansing feel without harsh drying. Post-cleanse skin feels soft and supported rather than stripped.
Wet face. Dispense a dime-sized amount, lather between palms. Apply to face and massage for 30 to 60 seconds. Rinse thoroughly. Use once or twice daily.
Modest. PDRN works better in leave-on products. For cleansing, the main benefit is the gentle surfactant base. PDRN is a supporting ingredient here.
Completely different. Rejuran is a clinical injection. medicube is topical cleansing. The topical is gentler but much weaker than clinical procedures.
Light makeup, yes. For heavy makeup, use an oil cleanser first.
3 to 4 months with twice-daily use.
No. PDRN is salmon-derived. Not vegan.
Pair with medicube PDRN Pink Niacinamide Toner for full PDRN routine, or browse the medicube collection.
Related: cleansers, PDRN products.
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