{"product_id":"parnell-panthenol-5-78-heartleaf-calming-serum-30ml-mirai-skin-parnell-panthenol-5-78-heartleaf-calming-serum-30ml","title":"Parnell Panthenol 5.78 Heartleaf Calming Serum 30ml","description":"\u003ch2\u003eParnell Panthenol 5.78 Heartleaf Calming Serum: Clinical-Strength Panthenol for Redness and Barrier Repair\u003c\/h2\u003e\n\u003cp\u003eParnell's Panthenol 5.78 serum is built around a specific, disclosed concentration of panthenol (provitamin B5) at 5.78%, paired with heartleaf extract (Houttuynia cordata), one of Korean skincare's most-validated calming botanicals. Most \"panthenol serums\" on the market use unspecified percentages well below 3%. Parnell's willingness to disclose 5.78% is unusual and reflects the brand's dermatology-clinic positioning.\u003c\/p\u003e\n\u003cp\u003ePanthenol at 5% plus is the concentration range with actual clinical data for wound healing, redness reduction, and barrier support. The heartleaf addition adds a second calming axis, targeting the inflammation pathways that drive acne flares and sensitized rosacea-pattern redness. This is a barrier repair serum with real dosing, designed for compromised, reactive, or post-procedure skin.\u003c\/p\u003e\n\u003ch3\u003eWhat It Does\u003c\/h3\u003e\n\u003cp\u003ePanthenol converts to pantothenic acid in skin, supporting epidermal cell function and water retention. At 5.78%, the serum produces measurable reduction in trans-epidermal water loss over 2 to 4 weeks. Heartleaf contributes anti-inflammatory and mild antimicrobial effects. The combination calms redness, supports healing of irritated skin, and improves barrier resilience. Not a brightening or anti-aging serum; a repair and maintenance serum.\u003c\/p\u003e\n\u003ch3\u003eWho It's For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSensitized or over-exfoliated skin:\u003c\/strong\u003e Rebuilds barrier over 4 to 6 weeks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRosacea-pattern redness:\u003c\/strong\u003e Calms diffuse redness without triggering flares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-procedure recovery:\u003c\/strong\u003e Safe after laser, peels, or microneedling once skin is closed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetinol or acid users:\u003c\/strong\u003e Buffer layer under or over actives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcne-prone skin in recovery:\u003c\/strong\u003e Supports healing of post-inflammatory marks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Specs\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eVolume: 30ml\u003c\/li\u003e\n\u003cli\u003ePrice: $34.20\u003c\/li\u003e\n\u003cli\u003eHero actives: 5.78% panthenol, heartleaf extract\u003c\/li\u003e\n\u003cli\u003eTexture: lightweight gel-serum, fast absorption\u003c\/li\u003e\n\u003cli\u003eFragrance: none\u003c\/li\u003e\n\u003cli\u003epH: 5.5, skin-matched\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eApply AM and PM after toner. Dispense 3 to 4 drops, press into damp skin. Wait 30 to 60 seconds, follow with moisturizer. For post-procedure use: apply twice daily starting 48 to 72 hours after treatment, once skin is closed. During active retinol integration, use this serum as the buffer layer underneath retinol.\u003c\/p\u003e\n\u003ch3\u003eFAQ\u003c\/h3\u003e\n\u003ch4\u003eWhy the specific 5.78% number?\u003c\/h4\u003e\n\u003cp\u003eIt reflects the exact formulation concentration rather than a marketing-rounded number. Parnell discloses this because clinical data on panthenol efficacy clusters around 5% plus. Lower concentrations (1 to 3%) are hydrating but not therapeutically meaningful for barrier repair.\u003c\/p\u003e\n\u003ch4\u003eHow does this compare to La Roche-Posay Cicaplast B5?\u003c\/h4\u003e\n\u003cp\u003eCicaplast B5 is a balm with 5% panthenol plus madecassoside in an occlusive base. Parnell's serum is a watery gel with 5.78% panthenol plus heartleaf. Cicaplast seals moisture on top; Parnell delivers more penetration. For raw, post-procedure skin: Cicaplast on top. For daily barrier support: Parnell underneath. Many users run both.\u003c\/p\u003e\n\u003ch4\u003eHow long until I see results?\u003c\/h4\u003e\n\u003cp\u003eRedness reduction: 3 to 7 days. Barrier feel: 1 to 2 weeks. Full repair cycle: 4 to 6 weeks.\u003c\/p\u003e\n\u003ch4\u003eCan I layer with retinol or vitamin C?\u003c\/h4\u003e\n\u003cp\u003eYes. Panthenol is non-reactive and buffers irritation. Apply this serum first, wait for absorption, then apply retinol or vitamin C. For sensitive users, this reverse-layering cuts retinol sting significantly.\u003c\/p\u003e\n\u003ch4\u003eIs this safe for rosacea?\u003c\/h4\u003e\n\u003cp\u003eGenerally yes. Panthenol and heartleaf are both on the short list of calming actives dermatologists recommend for rosacea. Patch test first, introduce once daily for the first week, then build to twice daily.\u003c\/p\u003e\n\u003ch3\u003eRelated Products\u003c\/h3\u003e\n\u003cp\u003ePair with Parnell Cicamanu pH Balanced Body Wash for body-wide calming, or any ceramide moisturizer as the sealing step. Browse the full Parnell collection and Korean calming serums.\u003c\/p\u003e\n","brand":"mirai-skin","offers":[{"title":"Default Title","offer_id":51741083336992,"sku":"53812902527348","price":13.68,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1004\/8333\/4432\/files\/fff3959796b79f67ea297d6fbccfab13.webp?v=1779694719","url":"https:\/\/usmirai-skin.com\/products\/parnell-panthenol-5-78-heartleaf-calming-serum-30ml-mirai-skin-parnell-panthenol-5-78-heartleaf-calming-serum-30ml","provider":"usmirai-skin.com","version":"1.0","type":"link"}